trial

  1. Nikki J

    Nurown 3b trial listing posted- not yet recruiting

    https://clinicaltrials.gov/study/NCT06973629?fbclid=IwY2xjawKTW-JleHRuA2FlbQIxMABicmlkETFad3FJeTIxVHJST3BUT1MyAR6uwLqwP7SKG5XfMHV2O_Fz1CfRPhHfmvU8okc3xz_gdu7zi8ESDMarmWWT6g_aem_EEwRgvLlSq8eupf4jla10Q
  2. P

    Novartis Phase 2 Trial - VHB937

    It looks like VHB937, being studied in the NCT06643481 clinical trial, targets microglia, which are immune cells in the nervous system. Specifically, VHB937 is designed to interact with a protein on the surface of microglia called TREM2 (Triggering Receptor Expressed on Myeloid Cells 2). The...
  3. JAM

    DiGAP trial

    Does anyone know whether Dr. Bedlack’s R.O.A.R DiGAP trial is taking place? In his Feb 2024 video he thought it was to start in a couple months at Duke. It was supposed to be a 9 month trial so I was wondering if it’s on going?
  4. JAM

    ? On EAP’s and trial drugs

    Do only some drugs that are currently in trials go to EAP? If so, why do only some and not all drugs in trials do it? How/why is it decided? I guess I have the same ? Regarding AA, why don’t all drugs that are going into a Ph 3 trial, or raising capital for Ph 3 go for AA (like Cline is...
  5. JAM

    Lighthouse ll, phase 3 trial

    I know this is currently on going, does anyone know when this trial is supposed to be completed? TIA
  6. Nikki J

    Webinar on clinical trial focus in Canada

    They did say they would discuss worldwide trials too but will be mostly Canadian https://research.als.ca/page/144453/subscribe/1?fbclid=IwY2xjawGHjB9leHRuA2FlbQIxMAABHcQ77KuAGcfddOACNcfxu0MPlUTwtZvtJldUHUZiZR4vMZY0wFzUaTaL4g_aem_2adHnhy6VrRdvMnPhDl98g
  7. P

    Thoughts on ILB, which may slow ALS progression, per data from small clinical trial

    Treatment with a high dose of ILB, an experimental injection therapy being developed by Tikomed, was well tolerated and appeared to slow the progression of amyotrophic lateral sclerosis (ALS) in a small clinical trial in the U.K. That’s according to data from the exploratory Phase 2 study...
  8. Nikki J

    TUDCA trial topline results

    As most of you know there was a European trial of TUDCA alone ( it is a component of Relyvrio). Topline results were negative. Announcement of top-line results - TUDCA ALS
  9. P

    Healey Trial - 2 Drugs Tested

    My brother, recently diagnosed with ALS, is going to get into the Healey Trial. Here's what they are currently testing. Anybody with experience with either of these drugs? DNL343 (Regimen G) Oral drug once daily taken with water or soft food Optional lumbar puncture 3:1 Active drug to placebo...
  10. lisa g

    Prime C trial

    Has anyone been getting the 2 medications in the prime c trial through a compounding pharmacy. Before Relyvrio was approved if you chose to pay out of pocket you could have it made by a compounding pharmacy. Was wondering if this was a possibility being both drugs used in the study are approved...
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