Edaravone survival

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Nikki J

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PALS
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04/2014
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MA
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This paper compares real world IV Edaravone patients with those who did not have it. Edaravone patients had increased survival.
 
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Thank you for sharing.
 
Just to be clear, this was a propensity matching study, in which real edaravone pts were matched against patients in the same claims database who didn't get the drug, using variables like age and gender to get some similarity. It was not a prospective trial where a patient shows up for the trial and is randomized to one arm or the other, which would be the gold standard.

Propensity scores are subject to a lot of noise , and esp. in ALS, traditional variables that are used for matching don't tell the whole story.
 
Sorry Nikki J I don’t see the link to the article
 
Did you click on the second word in the post ( paper)?

 
I have to say I barely saw that word was a link, it did not stand out well.
 
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